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Claiming Positive Results From Negative Trials: A Cause for Concern in Randomized Controlled Trial Research

Claiming Positive Results From Negative Trials: A Cause for Concern in Randomized Controlled Trial Research

were “active” - that both interventions were effective in facilitating or causing a change among participants. 

John A Cunningham

J Med Internet Res 2013;15(8):e179


The Systematic Removal of Participants Post-Randomization Can Lead to Alternate Explanations of the Results

The Systematic Removal of Participants Post-Randomization Can Lead to Alternate Explanations of the Results

This can introduce a potential confound or alternative explanation of the results. The recently published study by Rooke et al [1] removed participants from the analysis who reported other treatment use during the study (n=5).

John A Cunningham

J Med Internet Res 2013;15(6):e128