This paper is in the following e-collection/theme issue:

Diabetes Self-Management (484) Peer-to-Peer Support and Online Communities (636)

Published on in Vol 6, No 1 (2021): Jan-Mar

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/21611, first published .
Exchanges in a Virtual Environment for Diabetes Self-Management Education and Support: Social Network Analysis

Exchanges in a Virtual Environment for Diabetes Self-Management Education and Support: Social Network Analysis

Exchanges in a Virtual Environment for Diabetes Self-Management Education and Support: Social Network Analysis

Authors of this article:

Carlos A Pérez-Aldana1 Author Orcid Image ;   Allison A Lewinski2, 3 Author Orcid Image ;   Constance M Johnson1, 4 Author Orcid Image ;   Allison A Vorderstrasse5 Author Orcid Image ;   Sahiti Myneni1 Author Orcid Image
Article Authors Cited by (3) Tweetations (3) Metrics

    Original Paper

    1School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, United States

    2Durham Veterans Affairs Medical Center, Durham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham, NC, United States

    3Duke University School of Nursing, Durham, NC, United States

    4Cizik School of Nursing, The University of Texas Health Science Center at Houston, Houston, TX, United States

    5Rory Meyers School of Nursing, New York University, New York, NY, United States

    Corresponding Author:

    Carlos A Pérez-Aldana, MSc

    School of Biomedical Informatics

    The University of Texas Health Science Center at Houston

    Suite 600

    7000 Fannin

    Houston, TX, 77030

    United States

    Phone: 1 713 500 3900

    Email: Carlos.A.PerezAldana@uth.tmc.edu


    Background: Diabetes remains a major health problem in the United States, affecting an estimated 10.5% of the population. Diabetes self-management interventions improve diabetes knowledge, self-management behaviors, and clinical outcomes. Widespread internet connectivity facilitates the use of eHealth interventions, which positively impacts knowledge, social support, and clinical and behavioral outcomes. In particular, diabetes interventions based on virtual environments have the potential to improve diabetes self-efficacy and support, while being highly feasible and usable. However, little is known about the patterns of social interactions and support taking place within type 2 diabetes–specific virtual communities.

    Objective: The objective of this study was to examine social support exchanges from a type 2 diabetes self-management education and support intervention that was delivered via a virtual environment.

    Methods: Data comprised virtual environment–mediated synchronous interactions among participants and between participants and providers from an intervention for type 2 diabetes self-management education and support. Network data derived from such social interactions were used to create networks to analyze patterns of social support exchange with the lens of social network analysis. Additionally, network correlations were used to explore associations between social support networks.

    Results: The findings revealed structural differences between support networks, as well as key network characteristics of supportive interactions facilitated by the intervention. Emotional and appraisal support networks are the larger, most centralized, and most active networks, suggesting that virtual communities can be good sources for these types of support. In addition, appraisal and instrumental support networks are more connected, suggesting that members of virtual communities are more likely to engage in larger group interactions where these types of support can be exchanged. Lastly, network correlations suggest that participants who exchange emotional support are likely to exchange appraisal or instrumental support, and participants who exchange appraisal support are likely to exchange instrumental support.

    Conclusions: Social interaction patterns from disease-specific virtual environments can be studied using a social network analysis approach to better understand the exchange of social support. Network data can provide valuable insights into the design of novel and effective eHealth interventions given the unique opportunity virtual environments have facilitating realistic environments that are effective and sustainable, where social interactions can be leveraged to achieve diverse health goals.

    JMIR Diabetes 2021;6(1):e21611

    doi:10.2196/21611

    Keywords

    type 2 diabetes; diabetes education; self-management; social support; virtual environments; social network analysis 


    Overview

    Diabetes remains a major health problem in the United States, affecting an estimated 34.2 million people of all ages (about 10.5% of the country’s population) [1]. Data show that type 2 diabetes (T2D) accounts for the most diabetes burden (between 90% and 95%), and its prevalence will continue to increase [1,2]. Diabetes is a challenging chronic illness because self-management is critical to reduce and delay the onset of complications and mortality [3-6]. Several evidence-based strategies, such as diabetes self-management education (DSME) and ongoing self-management support by peers and providers, have been shown to be effective in the management of T2D [7-9]. In particular, self-management is important in T2D given that patients manage 99% of their own care [10,11]. Moreover, diabetes self-management interventions improve diabetes knowledge and self-management behaviors, in addition to clinical outcomes [12]. Despite these benefits, less than 60% of people with diabetes attend DSME and only about 7% of newly diagnosed patients with diabetes attend DSME within 12 months following their diagnosis [13-16], indicating a pressing need for the delivery of accessible DSME and ongoing self-management support interventions.

    Widespread internet connectivity provides new opportunities for wider web technology access and use by patients. Internet-based interventions, also known as eHealth, can connect patients to both peers and providers to facilitate support as well as access to evidence-based information [17]. Research suggests that T2D interventions incorporating interactive, individualized, and frequent interactions among patients, educators, and providers are among the most effective approaches [9]. eHealth interventions can provide such interactions in an effective and accessible way, which otherwise would be costly and unsustainable [12]. In addition, eHealth interventions have shown positive impacts on knowledge, social support, and clinical and behavioral outcomes [18]. Johnson et al have highlighted the benefits of eHealth interventions on T2D management, such as increased support, self-efficacy, and knowledge; improvements in glycemic levels and self-management behaviors; and efficient use of primary care services [12]. Furthermore, successful eHealth programs focused on DSME provided relevant content, engaging interactive elements, personalized learning experiences, and self-assessment tools for monitoring and feedback [17-20]. However, in spite of the potential benefits eHealth offers for DSME, eHealth interventions have been mostly based on traditional website formats. Such website formats generally lack realistic simulated environments where DSME actually takes place, such as patient community places (eg, grocery stores and restaurants) [7,21].

    Virtual Environments and Diabetes Self-Management Education and Support

    Virtual environments offer an effective way to provide patients with realistic settings for the acquisition and application of knowledge in community settings where daily T2D self-management takes place, while addressing barriers such as transportation, cost, time, and scheduling issues [22]. In addition, virtual environments have started to show a potential to improve diabetes self-efficacy and social support, while being highly feasible and usable [12]. Second Life (Linden Lab), a highly popular virtual world, has been shown to be an effective tool that can lead to “significant learning gains” [23]. Second Life allows users to socialize and behave in a similar way as they would naturally do in normal settings through virtual human representations known as avatars [24]. Furthermore, virtual environments, such as Second Life, offer the potential for users to perform behaviors within realistic scenarios by providing them with presence, immersion, and social interaction, while facilitating communication between patients, educators, and providers [12,24]. While virtual environments have been used to deliver health information, education, social support, and social networking, most Second Life–based health sites to date have focused on disseminating information and offering support groups [24].

    Self-management diabetes interventions based on virtual environments enable diabetes education, the development of new skills, and the exchange of peer support in synchronous and asynchronous ways [7]. The Second Life Impacts Diabetes Education & Self-Management (SLIDES) virtual community was among the first interventions aimed at providing DSME and support using Second Life [24]. The results of SLIDES showed improvements in diabetes self-efficacy, social support, and foot care, as well as trends toward improvements in diet, weight loss, and clinical outcomes, while being highly feasible and usable [12]. The development of the SLIDES platform, as well as its preliminary effects, is described elsewhere [12,24]. Virtual environments, such as SLIDES, are innovative ways to provide accessible DSME and ongoing self-management support. A key characteristic of these environments is the potential for participants to develop real-world skills via simulation and rehearsal within the virtual environment that can be transferable and thus affect behaviors in the real world [12].

    Another significant characteristic of virtual environments is the facilitation of social support among participants [12,24]. Social support is generally described as “an exchange of resources between at least two persons aimed at increasing the wellbeing of the receiver” [25-27]. Social support is recognized as a key component of diabetes self-management, in addition to adequate skills and behavioral development [22,28,29]. Studies have shown that social support is commonly provided through social interactions to achieve health outcomes [30,31]. Moreover, research suggests that people with T2D can benefit from frequent and sustained social interactions among peers and providers by obtaining education and support [28,32-34]. In addition, T2D interventions that are based on virtual environments can provide realistic, personalized, and ongoing interaction and support that assist participants in health care decision making [7,12,34-36]. SLIDES showed that virtual environment–mediated interactions resemble physical ones; therefore, patients with T2D are presented with the possibility of greatly improving their access to social support [12,34]. However, the social networks highlighting the patterns of interactions within T2D-specific virtual communities, such as SLIDES, have not been studied. While the prominent effects of social relationships on health decisions and related behavior changes have been established [37,38], little is known about social interactions and the exchange of support in disease-specific virtual environments.

    Social Network Analysis and Online Health Communities

    The study of social networks provides researchers with a unique opportunity to get an in-depth view and a better understanding of the structure of online communities [38,39]. Social network research has shown that social connections (ie, peers, family members, etc) disseminate health information, provide social support, and influence health behaviors [38,39]. Social network analysis (SNA) has been used to study the ways in which social connections can influence individuals’ attitudes, believes, and behaviors. Such network influences can be caused by the network environment, the position an individual occupies in the network, or structural or network-level properties [38,39]. For example, being central in a social network determines a high importance for information dissemination. Similarly, individuals located on a network’s periphery, known as peripheral individuals, can act as bridges connecting otherwise disconnected groups, thus enabling collective actions. Peripheral individuals are characterized by having one or few connections on the outside of a network and thus participating infrequently. Moreover, peripheral individuals are usually free from social norms and constraints, and thus, innovation can occur [38,39]. Furthermore, network structural properties, such as clustering, can help to identify highly connected groups of individuals, where behavior change can be accelerated. Lastly, densely connected networks have been shown to generate faster diffusion and increased coordinated action [38,39].

    SNA is increasingly becoming useful to the study of online health communities owing to the exponential growth in the use of electronic communications [40]. The massive amounts of social interactions taking place within online communities today are providing researchers with valuable network data. Research has focused on the analysis of online social interactions from both general purpose social media platforms (eg, Twitter and YouTube) and health care–specific platforms (eg, American Diabetes Association online community) [41-44]. Often, qualitative analysis and computational text analysis are used to analyze social media interactions [41-43]. Studies have shown that SNA provides insights into social influence, information dissemination, and behavioral diffusion [39,40,45,46]. On one hand, communication structure (who communicates with whom) is key for the study of peer influence on health behaviors [40]. On the other hand, analyses of the structures of online peer-to-peer communications provide valuable insights into opinion leaders [40,45,47]. Both approaches have the potential to help researchers model effective network data–based interventions [40]. Similarly, social support exchange patterns within disease-specific virtual communities, such as SLIDES, can be studied using a SNA approach, which would allow the visualization and description of communication structures, peer influences, and behavioral diffusion, as well as the impact on health outcomes, such as blood glucose levels, for patients with diabetes [45-50]. However, despite the benefits SNA offers, to our knowledge, social interactions occurring within virtual environments have not been studied using this approach. In this study, a secondary data analysis of SLIDES social interactions through the SNA lens was carried out to examine social support exchange patterns between participants and providers [12,24,34].

    Research Aims

    The overall goal of our study was to examine social support exchanges from a T2D self-management education and support intervention (SLIDES) that was delivered via a virtual environment. The specific aims of our study were as follows: (1) to examine patterns of social interaction and support of the SLIDES intervention by creating network structures for different types of social supports and assessing these support networks using quantitative network measures; (2) to explore the associations between social support network structures by correlating them with each other using the quadratic assignment procedure (QAP); and (3) to provide insights into the exchange of social support within a disease-specific virtual environment.


    SNA Methodology

    Social Network Data

    SLIDES social interaction data were used for our study [34]. SLIDES included a total sample of 24 individuals, with 20 participants and 4 providers (including diabetes educators and moderators). Detailed participant demographics are described elsewhere [12]. SLIDES facilitated virtual interactions among participants with T2D and providers in the following two types of sessions: education and support. Education sessions were held twice a week, and support sessions were held weekly. SLIDES social interactions consisted mostly of synchronous naturalistic conversations that took place throughout different locations within the virtual environment (eg, bookstore, restaurant, and classroom) [12,24]. These conversations enabled the exchange of social support among participants and between participants and providers, and were continuously recorded and transcribed [12,24]. These transcriptions provided the data set from which network data were derived for our analysis. Detailed information on the SLIDES study site, theoretical framework, sample, measures, and outcomes have been published elsewhere [12,24]. Our analysis focused on interactions where social support was exchanged among participants and between participants and providers during a 6-month study enrollment period [34]. Study participants could log into SLIDES and participate as much or as little as they wanted and engage in synchronous conversations. Social support was defined as “personal informal advice and knowledge that help individuals initiate and sustain T2D self-management behaviors, thus increasing adherence” [22,25,27,30,34]. Social support types included emotional, instrumental, informational, and appraisal [22,25-27,29,34]. SLIDES social interactions, which were previously characterized by the aforementioned types of social support [34,51], were used to create network structures in order to analyze social support exchange patterns at the group level (ie, participants/providers who interacted in a conversation by either listening or engaging directly, where a certain type of support was exchanged, were all linked together for that particular conversation). Thus, the unit of analysis included the tie among participants and between participants and providers who interacted via synchronous conversations, as well as the types of social support exchanged in each transcribed conversation as previously characterized [34,51].

    Network Structures and Measures

    Network structures were created for each type of social support by representing participants and providers as nodes and representing interactions where social support was exchanged as edges (interconnections between nodes). For each type of social support network, all edges indicating who participated in a conversation were included (ie, who interacted with whom during a virtual conversation in which social support was exchanged). Quantitative network measures were used to assess network structures across all types of social support. Network measures explain structural differences (eg, density and cohesion), as well as node importance within a network (eg, centrality) [38,39]. The following network measures were used: average degree (average number of connections of all nodes; a higher average degree number means that members of a network interacted with a higher number of members via synchronous conversations, either on a one-to-one basis or at a group level); graph density (proportion of connections relative to the total number of possible connections; ranging from 0 to 1; a higher graph density means that members of a network most likely engaged in conversations involving a higher number of members, ie, larger groups); average path length (average distance between all node dyads; the distance of a dyad is 1, which means a direct interaction between two members of the network; a higher average path length is associated with a higher distance or number of steps required for two network members to interact with each other, resulting in a less efficient network); average clustering coefficient (average measure of the interconnectivity of the node neighborhood; ranging from 0 to 1; a higher average clustering coefficient means that node neighborhoods are more interconnected, indicating conversations among a larger number of members for larger node neighborhoods); and modularity (the level of development of subcommunities within a network; ranging from −1 to 1; higher modularity values indicate higher levels of subcommunity development within a network) [38,39].

    Network Statistical Analysis

    Once network structures were created, we correlated them with each other to explore associations between social support network structures. The QAP was used to test network correlations. QAP is a nonparametric method based on permutations that allows testing structural similarities (correlations) between social network structures [52]. We used Gephi version 0.9.2 and UCINET version 6.685 (Analytic Technologies) to create network structures and to calculate network measures, as well as to perform correlation analysis [53,54].


    Network Structures

    Figure 1 shows a network structure depicting all SLIDES social interactions where all types of social support were exchanged among participants and between participants and providers. Network structures for each type of social support exchanged by SLIDES participants are shown in Figure 2.

    ‎
    Figure 1. Network structure of social interactions where all types of social supports were exchanged. Node size indicates degree and node color indicates the existence of three subcommunities or groups, with one larger subcommunity shown in orange and two smaller subcommunities shown in purple and grey. Further, edge thickness represents the frequency of interactions when members communicated more often.
    View this figure
    ‎
    Figure 2. Network structures of Second Life Impacts Diabetes Education & Self-Management (SLIDES) social support interactions by the type of support. Node size indicates degree and node color indicates the existence of subcommunities, where larger subcommunities are shown in orange and smaller subcommunities are shown in purple and grey.
    View this figure

    In addition, Table 1 summarizes the network measures for each social support network. As seen in Figure 2, the emotional and appraisal support networks were the most populous, with the former comprising 24 nodes and 1219 edges and the latter comprising 20 nodes and 737 edges. Moreover, the emotional and appraisal support networks had the highest average degrees (9.08 and 9.5, respectively) compared with the instrumental and informational support networks (6.0 and 3.2, respectively). This indicates that each member of these support networks interacted on average with nine other members via synchronous conversations, either on a one-to-one basis or at a group level, thus making them the most active networks. Additionally, assessment of degree at a node level showed that all support networks were somewhat centralized around a few nodes, suggesting that some members were more popular. Furthermore, the appraisal (0.5) and instrumental (0.43) support networks were the densest, suggesting that members of these networks most likely engaged in conversations involving a higher number of members (ie, larger groups), where some participants directly exchanged appraisal and/or instrumental support, while other members of the group had a latent exposure to this support.

    Table 1. Summary of social network metrics for Second Life Impacts Diabetes Education & Self-Management (SLIDES) social support networks.
    Social support networkAverage degreeGraph densityAverage path lengthClustering coefficientModularity
    Emotional9.080.391.740.730.11
    Instrumental6.00.431.620.760.12
    Informational3.20.351.980.570.46
    Appraisal9.50.51.520.720.12

    Additionally, no substantial differences were observed between all average path length values. However, the appraisal (1.52) and instrumental (1.62) support networks had a slightly lower average path length compared with the emotional (1.74) and informational (1.98) support networks. This indicates that the distance or number of steps needed for members of these networks to interact with each other required on average fewer steps to exchange the supports, thus making these networks more efficient. In terms of network structure and community development, on one hand, the instrumental, emotional, and appraisal support networks had higher average clustering coefficients (76%, 73%, and 72%, respectively) compared with the informational support network (57%). These results indicate high levels of interconnectivity within these support networks. On the other hand, the modularity values of the emotional (0.11), appraisal (0.12), and instrumental (0.12) support networks were lower compared with that of the informational (0.46) support network. This indicates that subcommunities of network members exchanging informational support reached higher levels of development in comparison with subcommunities from all other support networks.

    Lastly, Figure 3 illustrates a two-mode network representing the affiliation between participants and providers, and the types of social support exchanged via social interactions. As seen in Figure 3, according to degree, the two-mode network is centralized around emotional and appraisal support, indicating that a higher number of participants and providers participated in interactions where these types of support were exchanged (either directly or indirectly having a latent exposure as previously discussed). Moreover, a subgroup of participants and providers engaged more frequently in interactions where emotional support and appraisal support were exchanged, which are represented by thicker edges.

    ‎
    Figure 3. Two-mode network structure of social interactions for all types of support. The shape of the nodes distinguishes two sets of nodes as follows: squares represent participants and providers, and circles represent types of social support. In addition, the color of the circles represents each type of social support (orange, purple, yellow, and blue representing emotional, appraisal, informational, and instrumental support, respectively). Finally, the size of the circles indicates degree, and edge thickness represents the frequency of participants’ interactions within each type of support.
    View this figure

    Network Statistical Analysis

    Table 2 shows network correlation scores obtained by QAP analysis. All social support networks were correlated with one another. QAP correlation scores between the emotional and appraisal, instrumental and appraisal, and instrumental and emotional support networks were much stronger when compared with the correlations between the informational and appraisal, informational and emotional, and instrumental and informational support networks. The stronger correlation scores suggest that considerable similarities exist between the aforementioned social support networks.

    Table 2. Network correlation test results.
    VariableAppraisalEmotionalInformationalInstrumental
    Appraisal

    		Score10.9740.3440.833

    		P value—a<.001.004<.001
    Emotional

    		Score0.97410.3180.818

    		P value<.001—.003<.001
    Informational

    		Score0.3440.31810.204

    		P value.004.003—.02
    Instrumental

    		Score0.8330.8180.2041

    		P value<.001<.001.02—

    aNot applicable.


    Principal Findings

    In this study, we used SNA to examine patterns of social interactions and support of SLIDES, an intervention for T2D self-management education and support that was delivered via a virtual environment [12,24]. To the best of our knowledge, this study is among the first to explore the patterns of social interactions of a disease-specific virtual environment. This novel approach provided insights into the exchange of social support within the SLIDES virtual community. Our findings indicate that emotional and appraisal support networks were the largest, most centralized, and most active, indicating that a virtual community with a larger number of members can be more supportive. Moreover, a higher centralization indicated that some network members were more active, which suggests that a virtual community benefits from having active members, such as educators and moderators, because they can help engage the community. This is important for the design of interventions based on virtual environments. For example, interventions could recruit diabetes moderators or leaders to act as peer influencers or change agents. Moreover, appraisal and instrumental support networks are more connected than emotional and informational support networks. This suggests that more members are likely to engage in larger group synchronous conversations, thus indicating that well-connected networks can facilitate the exchange of appraisal and instrumental support within virtual communities. This finding could be leveraged when designing interventions that facilitate the exchange of appraisal and/or instrumental support.

    An analysis of the structures of the support networks revealed higher levels of interconnectivity within the instrumental, emotional, and appraisal support networks, as indicated by their higher average clustering coefficients. Clustering can accelerate information and behavior spread [38,39], thus suggesting that interventions based on virtual environments can leverage this characteristic to accelerate the exchange of social support. Despite high degrees of clustering, instrumental, emotional, and appraisal support networks had low modularity values, indicating low levels of subcommunity development. In contrast, the informational support network showed a higher level of subcommunity development. From an intervention’s perspective, subcommunities or groups within informational support networks can be leveraged to spread resources and behaviors, in addition to providing informational support. Studies have shown that groups have norms and exert social pressure, enabling behavior change, as well as more opportunities to access information, resources, and support [39].

    Our findings also show that a higher number of participants and providers participated in interactions where emotional support and appraisal support were exchanged, and they did so more frequently. These findings diverge from a previous analysis by Lewinski et al, where informational support and emotional support were the most commonly exchanged types of support among participants and between participants and providers, and appraisal support exchange was lower [34]. Their analysis focused on support exchanges at a dyadic level in order to characterize interactions. In contrast, our analysis focused on support exchanges at a group level, as previously indicated. In other words, a dyadic analysis for two participants who interact in a group conversation would identify the frequency of support exchanged between those two participants. On the other hand, our network approach to this same scenario would take into account the connections between all participants who engaged in the conversation, including those who actively engaged one another to exchange support, as well as the other participants who engaged passively and had a latent exposure. Taking this into account, we hypothesize that a higher and more frequent engagement in interactions where emotional and appraisal support were exchanged was caused by the role providers, specifically diabetes educators, played assisting in the self-management of diabetes.

    Lastly, network correlations showed that all social support networks were correlated with one another. Specifically, stronger correlation scores for emotional and appraisal, instrumental and appraisal, and instrumental and emotional support networks indicate that considerable similarities exist between these networks. These results suggest that SLIDES participants who exchanged emotional support were likely to exchange appraisal or instrumental support. Likewise, participants who exchanged appraisal support were likely to exchange instrumental support. From an intervention’s perspective, educators and moderators from virtual communities can leverage interactions where a certain type of support is exchanged in order to maximize the provision of advice and support among members of such communities. For example, by promoting interactions between members where emotional support is exchanged, further discussion and opportunities could be created that would most likely prompt exchange of appraisal or instrumental support [34,55,56]. As a result, a higher number of supportive relationships would be fostered among participants and providers, increasing the effectiveness of support networks and thus substantiating the value of virtual communities for diabetes self-management and other health goals.

    Limitations

    There are several limitations in this study. The small sample size of the SLIDES study (N=24) created a small virtual community, which consequently resulted in a small community. The social dynamics resulting from a small community might differ from larger ones, which suggests that our findings should be interpreted with caution. The creation of social networks from interactions, where some type of social support was exchanged, was considered at a group conversational level and not at a dyadic level. This resulted in group identification of social support interactions, meaning that a type of social support was assigned to all group participants interacting in a conversation where social support occurred during a particular conversation. Future studies could improve network creation by analyzing participants’ interactions at a dyadic level so that social support exchanges describe social ties at a dyadic level, thus providing more accurate social support dynamics. Despite these limitations, we consider these findings valuable because of the insights provided into social support exchanges within disease-specific virtual environments.

    Conclusions

    This study described the utility of SNA to examine social support in a DSME virtual environment. Our findings have revealed structural differences between support networks, as well as key network characteristics of supportive interactions facilitated by the virtual community, with emotional and appraisal networks being large, centralized, and most active, thus emphasizing the value of virtual environments as sources of these two support types for T2D patients. In addition, support networks have highlighted the benefits central members, such as educators and moderators, can contribute by facilitating community engagement. Specifically, educators and moderators from the SLIDES intervention have facilitated community engagement by leading weekly synchronous group meetings that include educational sessions, focusing on core American Diabetes Association/American Association of Diabetes Education self-management curriculum, as well as support sessions [12].

    Furthermore, our appraisal and instrumental support networks suggest that members of virtual communities are more likely to engage in larger group interactions where these types of support can be exchanged, with the caveat that some members can engage one another to actively exchange support, while the other members engage passively and have a latent exposure to support exchange. Lastly, our network correlation analysis has shown that participants who exchange emotional support are likely to exchange appraisal or instrumental support, and participants who exchange appraisal support are likely to exchange instrumental support. These associations suggest that interactions, where a certain type of support is exchanged, could be leveraged to maximize the provision of advice and support among network members, thus increasing the effectiveness of support networks enabled by virtual communities.

    Network data can provide valuable insights into the design of novel and effective digital health interventions given the unique opportunity disease-specific virtual environments have facilitating realistic environments that are effective and sustainable, where social interactions can be leveraged to achieve diverse health goals.

    Acknowledgments

    Data in this study were obtained in the following grants: F31-NR016622-01 (principal investigator [PI]: Lewinski) funded by the National Institutes of Health, National Institute for Nursing Research and 1R21LM010727-01 (PI: Johnson) funded by the National Library of Medicine. Support for Dr Lewinski was provided by the VA Office of Academic Affiliations (TPH 21-000), and publication support was provided by Durham VA Health Services Research Center of Innovation funding (CIN 13-410). Part of the research reported in this publication was supported by the National Library of Medicine of the National Institutes of Health under Award Number 1R01LM012974-01A1. The findings and conclusions in this document are those of the authors who are responsible for its contents and do not represent the views of the Department of Veterans Affairs or the National Institutes of Health; therefore, no statement in this article should be construed as an official position of the Department of Veterans Affairs.

    Conflicts of Interest

    AAL reports receiving funds from PhRMA Foundation and Otsuka. Other authors have no conflicts to declare.

    1. National Diabetes Statistics Report, 2020. Centers for Disease Control and Prevention. 2020.   URL: https://www.cdc.gov/diabetes/library/features/diabetes-stat-report.html [accessed 2020-11-30]
    2. Diabetes Report Card 2017. Centers for Disease Control and Prevention. 2018.   URL: https://www.cdc.gov/diabetes/pdfs/library/diabetesreportcard2017-508.pdf [accessed 2020-11-30]
    3. Diabetes Control Complications Trial Research Group, Nathan DM, Genuth S, Lachin J, Cleary P, Crofford O, et al. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993 Sep 30;329(14):977-986. [CrossRef] [Medline]
    4. Franz MJ, Pastors JG, Warshaw H, Daly AE. Does "Diet" Fail? Clinical Diabetes 2000;18(4):162-168 [FREE Full text]
    5. Lasker RD. The diabetes control and complications trial. Implications for policy and practice. N Engl J Med 1993 Sep 30;329(14):1035-1036. [CrossRef] [Medline]
    6. Murphy S, Xu J, Kochanek K. Deaths: final data for 2010. Natl Vital Stat Rep 2013 May 08;61(4):1-117. [Medline]
    7. Funnell MM, Anderson RM. Changing office practice and health care systems to facilitate diabetes self-management. Curr Diab Rep 2003 Apr;3(2):127-133. [CrossRef] [Medline]
    8. Norris SL, Engelgau MM, Narayan KM. Effectiveness of self-management training in type 2 diabetes: a systematic review of randomized controlled trials. Diabetes Care 2001 Mar;24(3):561-587. [CrossRef] [Medline]
    9. Vorderstrasse AA, Melkus GD, Pan W, Lewinski AA, Johnson CM. Diabetes Learning in Virtual Environments: Testing the Efficacy of Self-Management Training and Support in Virtual Environments (Randomized Controlled Trial Protocol). Nurs Res 2015;64(6):485-493 [FREE Full text] [CrossRef] [Medline]
    10. Funnell MM, Anderson RM. Patient empowerment: a look back, a look ahead. Diabetes Educ 2003;29(3):454-8, 460, 462 passim. [CrossRef] [Medline]
    11. Glasgow RE, Funnell MM, Bonomi AE, Davis C, Beckham V, Wagner EH. Self-management aspects of the improving chronic illness care breakthrough series: implementation with diabetes and heart failure teams. Ann Behav Med 2002;24(2):80-87. [CrossRef] [Medline]
    12. Johnson C, Feinglos M, Pereira K, Hassell N, Blascovich J, Nicollerat J, et al. Feasibility and preliminary effects of a virtual environment for adults with type 2 diabetes: pilot study. JMIR Res Protoc 2014 Apr 08;3(2):e23 [FREE Full text] [CrossRef] [Medline]
    13. Powers MA, Bardsley J, Cypress M, Duker P, Funnell MM, Fischl AH, et al. Diabetes self-management education and support in type 2 diabetes: a joint position statement of the American Diabetes Association, the American Association of Diabetes Educators, and the Academy of Nutrition and Dietetics. Diabetes Educ 2015 Aug 05;41(4):417-430. [CrossRef] [Medline]
    14. Fan L, Sidani S. Effectiveness of Diabetes Self-management Education Intervention Elements: A Meta-analysis. Canadian Journal of Diabetes 2009 Jan;33(1):18-26. [CrossRef]
    15. Diabetes Report Card 2014. Centers for Disease Control and Prevention. 2015.   URL: https://www.cdc.gov/diabetes/pdfs/library/diabetesreportcard2014.pdf [accessed 2020-11-30]
    16. Li R, Shrestha S, Lipman R, Burrows N, Kolb L, Rutledge S, Centers for Disease ControlPrevention (CDC). Diabetes self-management education and training among privately insured persons with newly diagnosed diabetes--United States, 2011-2012. MMWR Morb Mortal Wkly Rep 2014 Nov 21;63(46):1045-1049 [FREE Full text] [Medline]
    17. Kaufman N. Internet and information technology use in treatment of diabetes. Int J Clin Pract Suppl 2010 Feb(166):41-46. [CrossRef] [Medline]
    18. Murray E, Burns J, See TS, Lai R, Nazareth I. Interactive Health Communication Applications for people with chronic disease. Cochrane Database Syst Rev 2005 Oct 19(4):CD004274. [CrossRef] [Medline]
    19. Nijland N, van Gemert-Pijnen JE, Kelders SM, Brandenburg BJ, Seydel ER. Factors influencing the use of a Web-based application for supporting the self-care of patients with type 2 diabetes: a longitudinal study. J Med Internet Res 2011 Sep 30;13(3):e71 [FREE Full text] [CrossRef] [Medline]
    20. Ramadas A, Quek K, Chan C, Oldenburg B. Web-based interventions for the management of type 2 diabetes mellitus: a systematic review of recent evidence. Int J Med Inform 2011 Jun;80(6):389-405. [CrossRef] [Medline]
    21. Funnell M, Anderson R. Working toward the next generation of diabetes self-management education. American Journal of Preventive Medicine 2002 May;22(4):3-5. [CrossRef]
    22. Vorderstrasse A, Lewinski A, Melkus GD, Johnson C. Social Support for Diabetes Self-Management via eHealth Interventions. Curr Diab Rep 2016 Jul;16(7):56. [CrossRef] [Medline]
    23. Okita SY, Bailenson J, Schwartz DL. The Mere Belief of Social Interaction Improves Learning. 2007 Presented at: Proceedings of the Annual Meeting of the Cognitive Science Society; 2007; Nashville   URL: https://escholarship.org/uc/item/7rs81781
    24. Johnson C, Feenan K, Setliff G, Pereira K, Hassell N, Beresford HF, et al. Building a Virtual Environment for Diabetes Self-Management Education and Support. Int J Virtual Communities Soc Netw 2013;5(3) [FREE Full text] [CrossRef] [Medline]
    25. House J. Work stress and social support. Reading, MA: Addison-Wesley Publishing Company; 1981.
    26. Shumaker SA, Brownell A. Toward a Theory of Social Support: Closing Conceptual Gaps. Journal of Social Issues 1984;40(4):11-36. [CrossRef]
    27. Langford CPH, Bowsher J, Maloney JP, Lillis PP. Social support: a conceptual analysis. J Adv Nurs 1997 Jan 28;25(1):95-100. [CrossRef] [Medline]
    28. Steinsbekk A, Rygg L, Lisulo M, Rise MB, Fretheim A. Group based diabetes self-management education compared to routine treatment for people with type 2 diabetes mellitus. A systematic review with meta-analysis. BMC Health Serv Res 2012 Jul 23;12:213 [FREE Full text] [CrossRef] [Medline]
    29. Clark CM. Peer support in diabetes management -- toward global application. Overview. Fam Pract 2010 Jun 17;27 Suppl 1(suppl 1):i3-i5. [CrossRef] [Medline]
    30. Heaney CA, Israel BA. Social networks and social support. In: Glanz K, Rimer BK, Viswanath K, editors. Health behavior and health education: Theory, research, and practice. San Francisco, CA: Jossey-Bass; 2008:189-210.
    31. Chen L, Shi J. Social support exchanges in a social media community for people living with HIV/AIDS in China. AIDS Care 2015;27(6):693-696 [FREE Full text] [CrossRef] [Medline]
    32. Norris SL, Lau J, Smith SJ, Schmid CH, Engelgau MM. Self-management education for adults with type 2 diabetes: a meta-analysis of the effect on glycemic control. Diabetes Care 2002 Jul;25(7):1159-1171. [CrossRef] [Medline]
    33. Qi L, Liu Q, Qi X, Wu N, Tang W, Xiong H. Effectiveness of peer support for improving glycaemic control in patients with type 2 diabetes: a meta-analysis of randomized controlled trials. BMC Public Health 2015 May 06;15:471 [FREE Full text] [CrossRef] [Medline]
    34. Lewinski A, Anderson RA, Vorderstrasse AA, Fisher EB, Pan W, Johnson CM. Type 2 Diabetes Education and Support in a Virtual Environment: A Secondary Analysis of Synchronously Exchanged Social Interaction and Support. J Med Internet Res 2018 Feb 21;20(2):e61 [FREE Full text] [CrossRef] [Medline]
    35. Mitchell SE, Mako M, Sadikova E, Barnes L, Stone A, Rosal MC, et al. The comparative experiences of women in control: diabetes self-management education in a virtual world. J Diabetes Sci Technol 2014 Nov;8(6):1185-1192 [FREE Full text] [CrossRef] [Medline]
    36. Rosal MC, Heyden R, Mejilla R, Capelson R, Chalmers KA, Rizzo DePaoli M, et al. A Virtual World Versus Face-to-Face Intervention Format to Promote Diabetes Self-Management Among African American Women: A Pilot Randomized Clinical Trial. JMIR Res Protoc 2014 Oct 24;3(4):e54 [FREE Full text] [CrossRef] [Medline]
    37. Smith K, Christakis N. Social Networks and Health. Annu. Rev. Sociol 2008 Aug;34(1):405-429. [CrossRef]
    38. Valente TW. Social Networks and Health Behavior. In: Glanz K, Rimer BK, Viswanath K, editors. Health Behavior: Theory, Research, and Practice, 5th Edition. San Francisco, CA: Jossey-Bass; 2015:205-222.
    39. Valente TW. Social Networks and Health: Models, Methods, and Applications. New York, NY: Oxford University Press; 2010.
    40. Myneni S, Fujimoto K, Cohen T. Leveraging Social Media for Health Promotion and Behavior Change: Methods of Analysis and Opportunities for Intervention. In: Cognitive Informatics in Health and Biomedicine: Understanding and Modeling Health Behaviors. New York, NY: Springer International Publishing; 2017:315-345.
    41. Myneni S, Lewis B, Singh T, Paiva K, Kim SM, Cebula AV, et al. Diabetes Self-Management in the Age of Social Media: Large-Scale Analysis of Peer Interactions Using Semiautomated Methods. JMIR Med Inform 2020 Jun 30;8(6):e18441 [FREE Full text] [CrossRef] [Medline]
    42. Singh T, Wang J, Myneni S. Revealing Intention In Health-related Peer Interactions: Implications For Optimizing Patient Engagement In Self-health Management. 2020 Presented at: AMIA 2020 Virtual Annual Symposium; 2020; Virtual.
    43. Liu Y, Mei Q, Hanauer DA, Zheng K, Lee JM. Use of Social Media in the Diabetes Community: An Exploratory Analysis of Diabetes-Related Tweets. JMIR Diabetes 2016 Nov 07;1(2):e4 [FREE Full text] [CrossRef] [Medline]
    44. Fernandez-Luque L, Karlsen R, Melton GB. HealthTrust: a social network approach for retrieving online health videos. J Med Internet Res 2012 Jan 31;14(1):e22 [FREE Full text] [CrossRef] [Medline]
    45. Centola D. The spread of behavior in an online social network experiment. Science 2010 Sep 03;329(5996):1194-1197 [FREE Full text] [CrossRef] [Medline]
    46. Cobb NK, Graham AL, Abrams DB. Social network structure of a large online community for smoking cessation. Am J Public Health 2010 Jul;100(7):1282-1289 [FREE Full text] [CrossRef] [Medline]
    47. Christakis NA, Fowler JH. The collective dynamics of smoking in a large social network. N Engl J Med 2008 May 22;358(21):2249-2258 [FREE Full text] [CrossRef] [Medline]
    48. Myneni S, Cobb NK, Cohen T. Content-specific network analysis of peer-to-peer communication in an online community for smoking cessation. 2016 Presented at: AMIA Annual Symposium; 2016; Chicago, IL p. 934-943.
    49. Myneni S, Cobb NK, Cohen T. Finding meaning in social media: content-based social network analysis of QuitNet to identify new opportunities for health promotion. Stud Health Technol Inform 2013;192:807-811. [Medline]
    50. Cobb NK, Graham AL, Byron MJ, Niaura RS, Abrams DB, Workshop Participants. Online social networks and smoking cessation: a scientific research agenda. J Med Internet Res 2011 Dec 19;13(4):e119 [FREE Full text] [CrossRef] [Medline]
    51. Lewinski A, Anderson RA, Vorderstrasse AA, Fisher EB, Pan W, Johnson CM. Analyzing Unstructured Communication in a Computer-Mediated Environment for Adults With Type 2 Diabetes: A Research Protocol. JMIR Res Protoc 2017 Apr 24;6(4):e65 [FREE Full text] [CrossRef] [Medline]
    52. Krackhardt D. Predicting with networks: Nonparametric multiple regression analysis of dyadic data. Social Networks 1988 Dec;10(4):359-381. [CrossRef]
    53. Bastian M, Heymann SM, Jacomy M. Gephi: An Open Source Software for Exploring and Manipulating Networks. In: Proceedings of the Third International ICWSM Conference. 2009 Presented at: Third International ICWSM Conference; 2009; San Jose, CA   URL: https://www.aaai.org/ocs/index.php/ICWSM/09/paper/viewFile/154/1009
    54. Borgatti SP, Everett MG, Freeman LC. Ucinet for Windows: Software for Social Network Analysis. 2002 Dec 01.   URL: https://sites.google.com/site/ucinetsoftware/home [accessed 2020-12-01]
    55. Greenhalgh T, Collard A, Campbell-Richards D, Vijayaraghavan S, Malik F, Morris J, et al. Storylines of self-management: narratives of people with diabetes from a multiethnic inner city population. J Health Serv Res Policy 2011 Jan;16(1):37-43. [CrossRef] [Medline]
    56. Brundisini F, Vanstone M, Hulan D, DeJean D, Giacomini M. Type 2 diabetes patients' and providers' differing perspectives on medication nonadherence: a qualitative meta-synthesis. BMC Health Serv Res 2015 Nov 23;15:516 [FREE Full text] [CrossRef] [Medline]

    ‎
    DSME: diabetes self-management education
    QAP: quadratic assignment procedure
    SLIDES: Second Life Impacts Diabetes Education & Self-Management
    SNA: social network analysis
    T2D: type 2 diabetes

    Edited by D Griauzde; submitted 18.06.20; peer-reviewed by K Kloss, W Ahmed; comments to author 20.10.20; revised version received 04.11.20; accepted 18.11.20; published 25.01.21

    Copyright

    ©Carlos A Pérez-Aldana, Allison A Lewinski, Constance M Johnson, Allison A Vorderstrasse, Sahiti Myneni. Originally published in JMIR Diabetes (http://diabetes.jmir.org), 25.01.2021.

    This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Diabetes, is properly cited. The complete bibliographic information, a link to the original publication on http://diabetes.jmir.org/, as well as this copyright and license information must be included.