JMIR Diabetes

This research letter presents a cross-sectional analysis comparing the agreement of artificial intelligence models and nephrologists in responding to common patient questions about diabetic nephropathy.

Mobile health (mHealth) is a low-cost method to improve health for patients with diabetes seeking care in safety-net emergency departments, resulting in improved medication adherence and self-management. Additions of social support to mHealth interventions could further enhance diabetes self-management by increasing the gains and the postintervention maintenance.

Gestational diabetes mellitus and type 2 diabetes mellitus impose psychosocial burdens on pregnant individuals. As there is less evidence about the experience and management of psychosocial burdens of diabetes mellitus during pregnancy, we sought to identify these psychosocial burdens and understand how a novel smartphone app may alleviate them. The app was designed to provide supportive, educational, motivational, and logistical support content, delivered through interactive messages.

Background: Diabetic ketoacidosis (DKA) represents a significant and potentially life-threatening complication of diabetes, predominantly observed in individuals with type 1 diabetes (T1D). Studies have documented suboptimal adherence to diabetes management among children and adolescents, evidenced by deficient ketone monitoring practices.

Type 2 diabetes mellitus affects over 500 million people globally, with 10-20% requiring surgery. Diabetes patients are at increased risk for perioperative complications, including prolonged hospital stays and higher mortality, primarily due to perioperative hyperglycemia. Managing blood glucose during the perioperative period is challenging, conventional monitoring is often inadequate to detect rapid fluctuations. Clinical decision support systems (CDSS) are emerging tools to improve perioperative diabetes management by providing real-time glucose data and medication recommendations. This viewpoint examines the role of CDSS in perioperative diabetes care, highlighting their benefits and limitations. CDSS can help manage blood glucose more effectively, preventing both hyperglycemia and hypoglycemia. However, technical and integration challenges, along with clinician acceptance, remain significant barriers.

The use of digital health technology (DHT) in diabetes self-care is increasing, making electronic health (eHealth) literacy an important factor to consider among people with type 1 diabetes. There are very few studies investigating eHealth literacy among adults with type 1 diabetes, highlighting the need to explore this area further.

Type 2 diabetes mellitus (T2DM) has seen a continuous rise in prevalence in recent years, and a similar trend has been observed in the increased availability of glucose-lowering drugs. There is a need to understand the variation in treatment response to these drugs to be able to predict people who will respond well or poorly to a drug. Electronic health records, clinical trials, and observational studies provide a huge amount of data to explore predictors of drug response. The use of artificial intelligence (AI), which includes machine learning (ML) and deep learning (DL) techniques, has the capacity to improve the prediction of treatment response in patients. AI can assist in the analysis of vast datasets to identify patterns and may provide valuable information on selecting an effective drug. Predicting an individual’s response to a drug can aid in treatment selection, optimizing therapy, exploring new therapeutic options, and personalised medicine. This Viewpoint highlights the growing evidence supporting the potential of AI-based methods to predict drug response with accuracy. Furthermore, the methods highlight a trend toward using ensemble methods as preferred models in drug response prediction studies.

School-partnered interventions may improve health outcomes for children with type 1 diabetes, though there is limited evidence to support their effectiveness and sustainability. Family, school, or health system factors may interfere with intervention usability and implementation.

Technologies such as mobile apps, continuous glucose monitors (CGMs), and activity trackers are available to support adults with diabetes, but it is not clear how they are used together for diabetes self-management.

Since the rapid widespread uptake in 2020, the use of telemedicine to deliver diabetes specialty care has persisted. However, evidence evaluating patient and clinician perspectives on benefits, shortcomings, and approaches to improve telemedicine care for type 2 diabetes is limited.

Group-based diabetes care, both technology-enabled and in-person, can improve diabetes outcomes in low-income minority women, but the mechanism remains unclear.

Federally Qualified Health Centers (FQHCs) provide service to medically underserved areas and communities, providing care to over 32 million patients annually. The burden of diabetes is increasing, but often, the vulnerable communities served by FQHCs lag in the management of the disease due to limited resources and related social determinants of health. With the increasing adoption of technologies in health care delivery, digital tools for continuous glucose monitoring (CGM) are being used to improve disease management and increase patient engagement. In this viewpoint, we share insights on the implementation of a CGM program at an FQHC, the Community-University Health Care Center (CUHCC) in Minneapolis, Minnesota. Our intent is to improve diabetes management through better monitoring of glucose and to ensure that the CGM program enables our organization’s overarching digital strategy. Given the resource limitations of our population, we provided Libre Pro devices to uninsured patients through grants to improve health care equity. We used an interdisciplinary approach involving pharmacists, nurses, and clinicians and used hemoglobin A1c (HbA1c) levels as a measure of diabetes management. We assessed the CGM program and noted key aspects to guide future implementation and scalability. We recruited 148 participants with a mean age of 54 years; 39.8% (59/148) self-identified their race as non-White, 9.5% (14/148) self-identified their ethnicity as Hispanic or Latino, and one-third (53/148, 35.8%) were uninsured. Participants had diverse language preferences, with Spanish (54/148, 36.5%), English (52/148, 35.1%), Somali (21/148, 14.2%), and other languages (21/148, 14.2%). Their clinical characteristics included an average BMI of 29.91 kg/m2 and a mean baseline HbA1c level of 9.73%. Results indicate that the CGM program reduced HbA1c levels significantly from baseline to first follow-up (P<.001) and second follow-up (P<.001), but no significant difference between the first and second follow-up (P=.94). We share key lessons learned on cultural and language barriers, the digital divide, technical issues, and interoperability needs. These key lessons are generalizable for improving implementation at FQHCs and refining digital strategies for future scalability.